• Mirna Publications
• Further Reading

Mirna Publications

Scientific Reports

• Jason F. Wiggins, Lynnsie Ruffino, Kevin Kelnar, Michael Omotola, Lubna Patrawala, David Brown, and Andreas G. Bader
  Development of a Lung Cancer Therapeutic Based on the Tumor Suppressor MicroRNA-34 Cancer Res; 70(14); OF1–8
• Johnson, S. M., H. Grosshans, J. Shingara, M. Byrom, R. Jarvis, A. Cheng, E. Labourier, K. L. Reinert, D. Brown, and F. J. Slack. 2005.
  RAS is regulated by the let-7 microRNA family. Cell 120:635-47.
• Johnson, C. D., A. Esquela-Kerscher, G. Stefani, M. Byrom, K. Kelnar, D. Ovcharenko, M. Wilson, X. Wang, J. Shelton, J. Shingara, L. Chin, D. Brown, and F. J. Slack. 2007.
  The let-7 microRNA represses cell proliferation pathways in human cells. Cancer Res. 67:7713-22.
• Ovcharenko, D., K. Kelnar, C. Johnson, N. Leng, and D. Brown. 2007.
  Genome-scale microRNA and small interfering RNA screens identify small RNA modulators of TRAIL-induced apoptosis pathway. Cancer Res. 67:10782-8.
• Esquela-Kerscher, A., P. Trang, J. F. Wiggins, L. Patrawala, A. Cheng, L. Ford, J. B. Weidhaas, D. Brown, A. G. Bader, and F. J. Slack. 2008.
  The let-7 microRNA reduces tumor growth in mouse models of lung cancer. Cell Cycle 7: 759-64.
• Cogswell JP, Ward J, Taylor IA, Waters M, Shi Y, Cannon B, Kelnar K, Kemppainen J, Brown D, Chen C, Prinjha RK, Richardson JC, Saunders AM, Roses AD, Richards CA.
  Identification of miRNA changes in Alzheimer's disease brain and CSF yields putative biomarkers and insights into disease pathways. J Alzheimers Dis. 14: 27-41.
• Takeshita, F., Patrawala, L., Osaki, M., Takahashi, R. U., Yamamoto, Y., Kosaka, N., Kawamata, M., Kelnar, K., Bader, A. G., Brown, D., and T. Ochiya. 2009.
  Systemic Delivery of Synthetic MicroRNA-16 Inhibits the Growth of Metastatic Prostate Tumors via Downregulation of Multiple Cell-cycle Genes. Mol Ther.
• Trang, P., Medina, P. P., Wiggins, J. F., Ruffino, L., Kelnar, K., Omotola, M., Homer, R., Brown, D., Bader, A. G., Weidhaas, J. B., and F. J. Slack. 2009.
  Regression of murine lung tumors by the let-7 microRNA. Oncogene.

Review articles

• Pappas T. C., Bader, A. G., Andruss, B. F., Brown, D., and L. P. Ford. 2008.
  Applying small RNA molecules to the directed treatment of human diseases: realizing the potential. Expert Opin Ther Targets. 12: 115-27.